Weight loss is influenced by more than diet and exercise alone. Appetite regulation, insulin resistance, hormonal changes, sleep, stress, medications, and underlying medical conditions may all affect body weight. GLP-1–based injections can support weight management by reducing appetite and helping patients feel full with less food.
GLP-1 is a naturally occurring hormone involved in appetite regulation, digestion, and blood glucose control. GLP-1–based medications imitate or enhance these signals, helping reduce hunger and calorie intake.
Wegovy and Saxenda are GLP-1 receptor agonists. Mounjaro contains tirzepatide, which acts on both GIP and GLP-1 receptors. Although they work in related ways, the medications differ in their active ingredient, injection schedule, dose-escalation plan, expected response, and approved indications.
GLP-1–based medications act on appetite-regulating areas of the brain and help patients feel satisfied after eating smaller amounts. They may also slow stomach emptying and improve glucose-dependent insulin regulation.
These effects may help with:
Tirzepatide additionally activates GIP receptors and may improve insulin sensitivity and glucose regulation. Individual results vary, and greater weight loss is not always the safest or most appropriate treatment goal.
The amount of weight lost varies among individuals, but clinical studies have shown meaningful average reductions in body weight when these medications are used alongside nutrition and physical activity.
The figures above are based on separate clinical trials and are not a direct comparison of the three medications. Individual results depend on factors such as dose, treatment duration, starting weight, lifestyle, tolerability, and adherence.
| Injection Type | About Injection |
|---|---|
| Saxenda | Saxenda contains liraglutide and is injected once daily. One pen typically lasts about one week at the maintenance dose. As with other GLP-1 medications, the dose is gradually increased. Because it is administered daily, it may be suitable for patients who prefer closer day-to-day dose management or for whom a weekly medication is not appropriate. |
| Wegovy | Wegovy contains semaglutide and is injected once weekly. One pen provides four once-weekly doses for four weeks. Treatment normally begins at a low dose and is gradually increased to reduce gastrointestinal side effects. It may be considered for adults with obesity or for certain adults who are overweight and have weight-related health risks. The final dose and pace of escalation depend on treatment response and tolerability. |
| Mounjaro | Mounjaro contains tirzepatide and is injected once weekly. One pen provides four once-weekly doses for four weeks. It activates both GIP and GLP-1 receptors, helping regulate appetite, blood glucose, and energy intake. In Korea, Mounjaro is approved for both type 2 diabetes treatment and chronic weight management in eligible adults with obesity or overweight. Treatment begins at a low dose and is gradually increased according to response and tolerability. |
Weight loss injections may be considered for adults who:
A low body weight, cosmetic desire alone, or a request for rapid short-term weight loss does not automatically mean that medication is appropriate.
Body weight and reproductive health are closely connected. Insulin resistance and excess weight may contribute to irregular menstruation, ovulatory dysfunction, PCOS symptoms, fertility concerns, and increased metabolic risk. Weight may also change during postpartum recovery, perimenopause, and menopause.
An OB/GYN assessment can help determine whether weight gain may be associated with:
At LANTE OBGYN, treatment is planned with consideration of both weight-management goals and women’s reproductive and hormonal health. When indicated, pelvic ultrasound examinations, hormone testing, metabolic blood tests, or other evaluations may be recommended.
Depending on the patient’s condition and goals, care may also include prescription weight-loss medications, food diary review and dietary guidance, weight-management injections, and supportive IV therapy.
Before prescribing medication, the doctor will review your current height, weight, and BMI, previous weight changes and weight-loss attempts, medical and surgical history, and any medications or supplements you are taking. A history of diabetes, gallbladder, pancreatic, kidney, or gastrointestinal conditions, as well as a personal or family history of certain thyroid cancers, may also be considered.
For women, menstrual patterns, hormone-related symptoms, current contraception, pregnancy or breastfeeding status, and future pregnancy plans are also important when planning treatment. Blood tests may be recommended depending on the patient’s condition, but the same tests are not required for everyone.
Weight loss injections are generally started at a low dose and gradually increased while treatment response and side effects are monitored. Increasing the dose too quickly may worsen nausea, vomiting, abdominal discomfort, or other gastrointestinal symptoms.
During follow-up, the doctor may review appetite and food intake, changes in weight and body composition, gastrointestinal side effects, hydration and bowel habits, and any menstrual or hormonal changes. Based on these findings, the dose may be maintained, increased, reduced, or discontinued.
The highest available dose is not necessary or appropriate for every patient. Treatment should be individualized according to both effectiveness and tolerability.
Common side effects may include:
Symptoms are often more noticeable when treatment begins or when the dose is increased. Eating smaller portions, avoiding heavy meals, maintaining hydration, and following the prescribed escalation schedule may help.
Severe or persistent abdominal pain, repeated vomiting, dehydration, symptoms of an allergic reaction, or other significant symptoms require medical evaluation. GLP-1–based medications may not be suitable for patients with certain thyroid, pancreatic, gallbladder, gastrointestinal, or other medical conditions.
Weight loss injections should not be used during pregnancy. Patients who are pregnant, breastfeeding, actively trying to conceive, or planning pregnancy should inform the doctor before starting treatment.
Semaglutide (Wegovy) remains in the body for an extended period and is generally discontinued at least two months before a planned pregnancy. Other medications may have different discontinuation recommendations.
Tirzepatide (Mounjaro) may temporarily reduce the effectiveness of oral hormonal contraceptives by delaying gastric emptying. Patients taking oral contraceptive pills may be advised to use a non-oral contraceptive method or an additional barrier method for four weeks after starting treatment and for four weeks after each dose increase.
During weight loss, some reduction in lean body mass and muscle mass may occur along with fat loss. This is generally understood as a possible part of the weight-loss process rather than evidence that GLP-1–based medications directly damage muscle.
Adequate protein intake, regular resistance exercise, and an appropriate rate of weight loss are therefore important. Depending on the patient’s goals, medical weight management may be combined with nutritional guidance, strength training, or non-invasive body-contouring treatment to support muscle conditioning and improve body shape.
Medication and body-contouring treatments serve different purposes and should not be considered interchangeable.
EMS Body Contouring (Accurcurv)The cost of Weight Loss Injection treatment in Seoul varies depending on the medication, prescribed dose, treatment duration, and any consultations, examinations, or laboratory tests required.
• Saxenda: KRW 130,000~ per pen
• Wegovy 0.25 mg: KRW 310,000~ per pen
• Mounjaro 2.5 mg: KRW 350,000~ per pen
Prices for Wegovy and Mounjaro increase at higher doses.
Consultation fees, examinations, blood tests, and other treatment-related charges may apply separately. Medication availability and prices are subject to change.
Reviewed by Lante’s female OBGYN specialists, who personally perform intimate aesthetic surgery. For general information only. It does not replace an in-person consultation. Last reviewed: 16 Oct 2026.
Effective weight management is not based on medication alone. At LANTE OBGYN, treatment begins with an in-person consultation and considers weight history, metabolic health, menstrual and hormonal symptoms, current contraception, and future pregnancy plans.
Visit our English-speaking OB/GYN clinic in Gangnam, Seoul for an individualized assessment and weight-management plan.
Female board-certified specialists handle consultation, surgery, and aftercare — performed personally by a specialist, in a private setting.
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Current page summary: GLP-1 based injections reduce appetite and increase fullness to support weight management. This page explains what it is, who it may be considered for, how it is evaluated and performed, what to expect afterwards, cost at the clinic in Gangnam, Seoul, and answers the questions patients ask most often.
Clinic: LANTE OBGYN
Official URL: https://lanteobgynseoul.com/
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